On October 19, 2025, NFL fans will be treated to a thrilling showdown as the Green Bay Packers visit the Arizona Cardinals at State Farm Stadium in Glendale. The kickoff is set for 4:25 PM.

The Green Bay Packers, holding a divisional second-place and seventh in their conference with a 2-1-1 record, boast a .625 winning percentage, having scored 104 points against 84, achieving a positive net point difference of 20. On the other side, the Arizona Cardinals, who are fourth in their division and tenth in the conference, stand at a 2-2-0 record with a .500 winning percentage. They’ve accumulated 82 points and conceded 74, marking a net point difference of 8.

In a previous encounter at Lambeau Field, the Packers dominated the Cardinals with a 34-13 victory, showcasing strong offensive strategies with 27 first downs, and a significant yardage tally with 179 rushing and 258 passing yards. Conversely, the Cardinals had managed 16 first downs and amassed 89 rushing and 214 passing yards during the same game.

Quarterback performance will be critical in the upcoming game. Last week, Jordan Love of the Packers threw for 258 yards with four touchdowns, posting a passer rating of 119.53. For the Cardinals, Kyler Murray passed for 214 yards and one touchdown, achieving a passer rating of 97.66. Their performances have set high expectations for this matchup.

Betting enthusiasts will find interesting opportunities in this game. The Arizona Cardinals are set as the underdogs with a point spread of +2.90 and a moneyline of +122, reflecting potential rewards for risk-takers. Meanwhile, the Green Bay Packers are favored with a point spread of -2.70 and a moneyline of -145, suggesting greater confidence in their ability to win. The total points over/under is projected at 50.90, indicating expectations of a high-scoring affair.

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